Isaac & Miria

Isaac Dian (アイザック·ディアン Aizakku Dian) and Miria Harvent (ミリア·ハーヴェント Miria Hāvento) are the bumbling thief couple of Baccano!.

Biography
Isaac and Miria are a pair of clueless and eccentric partner-in-crime lovers who dress up in costumes and commit strange robberies - such as stealing candy and even the entrance door of a museum (so people "couldn't enter there anymore") - in Prohibition-era United States. In 1930, the duo attempt to steal the entire household of the mafia families of Genoard (which they succeed) and Martillo, incident on which they become unintentionally immortal after mistaking the Grand Panacea for alcohol and drinking it at a celebration. The next year, they board the Flying Pussyfoot express train and survive the bloody hijacking that occurs. Isaac is arrested for various thefts in 1934 and imprisoned on Alcatraz, but released in the same year, later reuniting with Miria. The pair continue to live happily, finally realizing they are immortal 67 years later, in 2001, after stealing some cellphones in Manhattan.

Abilities
Immortality aside, they possess a striking amount of luck, having escaped numerous dangerous situations throughout the series without serious injury (it took them roughly 70 years to realize they were immortal). They're both very charismatic and "sprinkle happiness without noticing." They also exhibit a somewhat indomitable will as is suggested by their headstrong personalities.

Trivia

 * They resemble the real-life thief duo Bonnie and Clyde, being possibly based on their example as an inverse parallel to them (Bonnie and Clyde robbed for money and enjoyed killing).
 * Numerous publications in various media have been written on the subject of Isaac and Miria's characters. Most described them as the most entertaining characters and commented on how the series would not be the same without them. One reviewer felt that they are the protagonists of the series, which features an ensemble cast. They were awarded "Duo of the Year" in 2009 by Anime News Network.
 * Isaac and Miria appear in the series' two drama CDs, where they survive the Flying Pussyfoot incident in 1931 Local Chapter ・ Express Chapter The Grand Punk Railroad and hope to meet true revolutionaries in a small Mexican village in Firo Prochainezo witnesses the 53rd death of Pietro Gonzalez.
 * They are playable characters in the video game and characters in the two-volume manga.
 * The pair also made a brief appearance in an episode of the Durarara!! anime series, during which they are in modern-day Ikebukuro, Tokyo and attend the first meeting of the Dollars, an anonymous online gang. This seems to settle a debate over wether the worlds of Baccano! and Durarara!! are connected. They also appeared in the following OVA episode seperate from the main series, where they comment on the supposed UFOs seen shooting across the sky. These are actually yakuza members covered in paint that were thrown out a three story window by Heiwajima Shizuo.